We send out your mail server details in your cPanel hosting confirmation and these are the same across all email client programs. Please locate this hosting confirmation so you have your basic settings in front of you and then you can find instructions on setting up email in the most popular email clients/devices by following the links. The exact wording may vary from version to version:
Mac Mail
Outlook
Thunderbird
Gmail
iPhone & iPad
Android
If you are having issues after going through the basic set up instructions (you are getting an error trying to connect to either your incoming or outgoing mail server or both) take a look at our entry on troubleshooting problems in your email client.